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Topical
FDA-approved for hair loss

Minoxidil (Topical)

Generic name: minoxidil

An over-the-counter vasodilator applied directly to the scalp. Available in 2% and 5% concentrations; the 5% formulation is more effective in trials.

Informational only; consult a clinician. This content does not constitute medical advice and is not a substitute for professional diagnosis or treatment.

Typical dose

1 mL of 5% solution, twice daily

Cash-pay price

$10 - $25/mo

Evidence level

Strong

What it is

Topical minoxidil is an over-the-counter treatment applied directly to the scalp, available in 2% and 5% concentrations. Originally developed as an oral blood-pressure medication, its hair-growth properties were discovered as a side effect. It is FDA-approved for androgenetic alopecia and is one of the most widely used hair loss treatments worldwide.

Who it's commonly used by

Topical minoxidil is used by both men and women experiencing pattern hair loss. The 5% concentration is approved for men; the 2% concentration is approved for women. It is most effective for diffuse thinning, particularly at the vertex (crown). Those with recent-onset thinning tend to respond better than those with long-standing hair loss.

Typical timeline

Initial shedding (sometimes called 'dread shed') may occur in the first 2 to 8 weeks as resting hairs are pushed out by new growth. Visible improvement typically begins between 3 and 6 months of consistent twice-daily application. Maximum benefit is usually reached at 12 months. Like finasteride, benefits depend on continued use.

Common side effects

Topical minoxidil is generally well tolerated. The most frequently reported effects are local in nature.

  • Scalp irritation or dryness
  • Flaking at the application site
  • Increased facial hair (more common in women)
  • Temporary increase in shedding during first weeks
  • Headache (uncommon)
  • Lightheadedness (rare)

Questions to ask a clinician

Even though topical minoxidil is available over the counter, a clinician can help you use it more effectively.

  • Should I use the 2% or 5% concentration?
  • Is once-daily application sufficient, or should I apply twice daily?
  • Can I combine topical minoxidil with other treatments?
  • How long should I continue if I don't see results?
  • Are there signs that would indicate I should stop using it?
  • Does the foam or solution formulation matter?

Sources

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